An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect
Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice - ScienceDirect
Chemogenetics drives paradigm change in the investigation of behavioral circuits and neural mechanisms underlying drug action - ScienceDirect
New Technologies for Elucidating Opioid Receptor Function: Trends in Pharmacological Sciences
Brain Sciences | Free Full-Text | Delta Opioid Receptors and Enkephalinergic Signaling within Locus Coeruleus Promote Stress Resilience
Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats | Neuropsychopharmacology
Frontiers | Dynorphin/kappa opioid receptor system regulation on amygdaloid circuitry: Implications for neuropsychiatric disorders
Frontiers | Knock-In Mouse Models to Investigate the Functions of Opioid Receptors in vivo
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System
The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice | Scientific Reports
Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges | Pharmacological Reviews
Clozapine N-Oxide Administration Produces Behavioral Effects in Long–Evans Rats: Implications for Designing DREADD Experiments | eNeuro
Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats | Neuropsychopharmacology
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Combining designer receptors exclusively activated by designer drugs and neuroimaging in experimental models: A powerful approach towards neurotheranostic applications - Peeters - 2020 - British Journal of Pharmacology - Wiley Online Library
![PDF] DREADDs for Neuroscientists | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/cc7db00617d97220b2f596e27279d1b9ea9bcf59/6-Figure3-1.png "PDF] DREADDs for Neuroscientists | Semantic Scholar")
PDF] DREADDs for Neuroscientists | Semantic Scholar
Psychoactives | Free Full-Text | The Role of the Dynorphin/Kappa Opioid Receptor System in the Actions of Alcohol
PDF) A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior
An Overview of Chemogenetics
Usefulness of knockout mice to clarify the role of the opioid system in chronic pain - Maldonado - 2018 - British Journal of Pharmacology - Wiley Online Library
Dynorphin / kappa-opioid receptor regulation of excitation-inhibition balance toggles afferent control of prefrontal cortical circuits in a pathway-specific manner | Molecular Psychiatry
Ligand and G-protein selectivity in the κ-opioid receptor | Nature
Kappa-opioid receptor stimulation in the nucleus accumbens shell: Differential effects across the rostro-caudal axis on dopamine transmission and affective behavior | bioRxiv
